Developmental and regional expression of mRNAs encoding sodium-dependent and facilitative glucose transporter proteins in human fetal and Grownup little intestine was examined by Davidson and colleagues.105 The abundance of mRNAs encoding the sodium glucose co-transporter isoform SGLT1 and also the facilitative glucose transporter isoforms GLUT2 and GLUT5 exhibited optimum levels in adult little intestine, though the levels of GLUT1 mRNA had been observed to be larger in fetal than in Grownup small intestine. Immunohistochemical Examination with the fetal modest intestine confirmed that GLUT5 was localized along the intercellular junctions on the creating villus. Wang and coworkers68 섹세게이밍 also demonstrated expression of sodium-dependent glucose transporter mRNA while in the tiny intestine of fetuses between nine and eighteen weeks of gestational age. The sodium-dependent glucose transporter mRNA is likewise expressed inside the fetal colon but in decrease amounts than during the Grownup colon.
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